Caring or daring? Exploring the impact of facial masculinity/femininity and gender category information on first impressions

In two studies we disentangled and systematically investigated the impact of subtle facial cues to masculinity/femininity and gender category information on first impressions. Participants judged the same unambiguously male and female target persons–either with masculine or feminine facial features slightly enhanced–regarding stereotypically masculine (i.e., competence) and feminine (i.e., warmth) personality traits. Results of both studies showed a strong effect of facial masculinity/femininity: Masculine-looking persons were seen as colder and more competent than feminine-looking persons. This effect of facial masculinity/femininity was not only found for typical (i.e., masculine-looking men and feminine-looking women) and atypical (i.e., masculine-looking women and feminine-looking men) category members; it was even found to be more pronounced for atypical than for typical category members. This finding reveals that comparing atypical members to the group prototype results in pronounced effects of facial masculinity/femininity. These contrast effects for atypical members predominate assimilation effects for typical members. Intriguingly, very subtle facial cues to masculinity/femininity strongly guide first impressions and may have more impact than the gender category

Faced with exclusion: Perceived facial warmth and competence influence moral judgments of social exclusion

The current research investigates how facial appearance can act as a cue that guides observers' feelings and moral judgments about social exclusion episodes. In three studies, we manipulated facial portraits of allegedly ostracized persons to appear more or less warm and competent. Participants perceived it as least morally acceptable to exclude a person that appeared warm-and-incompetent. Moreover, participants perceived it as most acceptable to exclude a cold-and-incompetent looking person. In Study 2, we also varied the faces of the excluding group (i.e., the ostracizers). Results indicate that typical ostracizers are imagined as cold-and-incompetent looking. Study 3 suggests that the effect of a target's facial appearance on moral judgment is mediated by feelings of disgust. In sum, people's moral judgment about social exclusion can be influenced by facial appearance, which has many implications in intergroup research, such as for bystander intervention

Chance Mehrsprachigkeit: Latein als sozialer Katalysator

Das 2016 in den Schweizer Halbkantonen Basel-Stadt und Basel-Landschaft konzipierte Fach Lingua Latein hat zum Ziel, über das Lernen von Latein im ständigen Vergleich mit modernen Sprachen die intuitiven und metakognitiven Sprachenkompetenzen leistungsmäßig heterogener Lerngruppen zu fördern. Die Auswertung einer 2017–2019 durchgeführten Studie liegt nun vor: Bei 104 Lernenden wurden im Verlauf zweier Schuljahre wiederholt ihre Kompetenzen im Deutschen und in anderen modernen Sprachen gemessen und der Zusammenhang dieser Kompetenzen mit ihrem sozioökonomischen Status (SES) und ihrer Sprachenkonstellation analysiert. Die intuitiven und metakognitiven sprachlichen Kompetenzen aller Lernenden stiegen signifikant an. Die Abhängigkeit der Leistungen vom SES nahm signifikant ab, indem die Sprachenkompetenzen der mehrsprachigen Lernenden, die zugleich auch niedrigeren SES hatten, gezielt aktiviert wurden. Die Selbsteinschätzung der Lernenden entsprach diesen Ergebnissen nicht, was möglicherweise mit den niedrigen Erwartungen der Lernenden an experimentelle, spielerische Lernformen zusammenhängt sowie mit der internalisierten Konnotation von Mehrsprachigkeit mit niedrigem SES und daraus resultierenden schwächeren Leistungen

Differences in faces do make a difference: Diversity perceptions and preferences in faces

Throughout previous research focusing on individuals' diversity perception, it remains somewhat unclear which attributes (i.e., objective diversity) are reflected in perceptions of diversity. This manuscript investigates whether individuals consider objective differences in ambiguous facial information (which are not related to gender or race) when making diversity judgments and decisions. Throughout seven studies, facial information of group members was manipulated to appear more similar or different in regards to personality and information unrelated to Big 5 dimensions, while race, gender, and age were kept constant. Study 1a provides support that objective differences in facial information related to perceived personality traits is validly reflected in perceptions of diversity. Study 1b shows that results regarding the Big 5 can be replicated in an ensemble-coding setup. Studies 2a and 2b replicate this result, additionally showing that objective differences in facial information unrelated to the Big 5 are reflected in perceptions of diversity, too. Focusing on perceived extraversion, Study 3 reveals that individuals select faces differing (similar) in extraversion information in order to assemble a diverse (homogeneous) team. Study 4 investigates diversity choices in an ambiguous setting, showing that individuals who more strongly believe in the value of diversity are more likely to assemble a team that is objectively diverse regarding facial information. Study 5 indicates that the association between diversity in facial information and choices deteriorates if other attributes such as gender are varied too. The impact of the results for research is highlighted and discussed

The Basel Face Database: A validated set of photographs reflecting systematic differences in Big Two and Big Five personality dimensions

Upon a first encounter, individuals spontaneously associate faces with certain personality dimensions. Such first impressions can strongly impact judgments and decisions and may prove highly consequential. Researchers investigating the impact of facial information often rely on (a) real photographs that have been selected to vary on the dimension of interest, (b) morphed photographs, or (c) computer-generated faces (avatars). All three approaches have distinct advantages. Here we present the Basel Face Database, which combines these advantages. In particular, the Basel Face Database consists of real photographs that are subtly, but systematically manipulated to show variations in the perception of the Big Two and the Big Five personality dimensions. To this end, the information specific to each psychological dimension is isolated and modeled in new photographs. Two studies serve as systematic validation of the Basel Face Database. The Basel Face Database opens a new pathway for researchers across psychological disciplines to investigate effects of perceived personality

Who gets ostracized? A personality perspective on risk and protective factors of ostracism

Ostracism, excluding and ignoring others, results from a variety of factors. Here, we investigate the effect of personality on the likelihood of becoming a target of ostracism. Theorizing that individuals low in conscientiousness or agreeableness are at risk of getting ostracized, we tested our hypotheses within five pre-registered studies: Four experiments investigating participants' willingness to ostracize targets characterized by different personality traits and a reverse correlation face modelling study where we determined and subsequently validated the stereotypical face of an ostracized person. A survey study within a representative German data panel further corroborated our findings. In line with our hypotheses, persons low in conscientiousness or agreeableness provoke more ostracism intentions (Studies 1, 2, and 4), are more likely to be actually ostracized by others (Study 3), represent the stereotype of an "ostracizable" person (Study 5), and report experiencing more ostracism (Study 6). Effects remained stable even after controlling for likeability of the target (Study 2 and 4). Moreover, being described as negative on one personality dimension could not be compensated by being described as positive on the other (Study 4). In exploratory analyses, we further investigated the effects of openness to experience, neuroticism and extraversion. In sum, we find evidence that personality affects the likelihood of becoming a target of ostracism, and that especially low agreeableness and conscientiousness represent risk factors

Modeling Local Coherence: An Entity-Based Approach

This article proposes a novel framework for representing and measuring local coherence. Central to this approach is the entity-grid representation of discourse, which captures patterns of entity distribution in a text. The algorithm introduced in the article automatically abstracts a text into a set of entity transition sequences and records distributional, syntactic, and referential information about discourse entities. We re-conceptualize coherence assessment as a learning task and show that our entity-based representation is well-suited for ranking-based generation and text classification tasks. Using the proposed representation, we achieve good performance on text ordering, summary coherence evaluation, and readability assessment. 1

Deciphering the Role of a SLOG Superfamily Protein YpsA in Gram-Positive Bacteria

Bacteria adapt to different environments by regulating cell division and several conditions that modulate cell division have been documented. Understanding how bacteria transduce environmental signals to control cell division is critical in understanding the global network of cell division regulation. In this article we describe a role for Bacillus subtilis YpsA, an uncharacterized protein of the SLOG superfamily of nucleotide and ligand-binding proteins, in cell division. We observed that YpsA provides protection against oxidative stress as cells lacking ypsA show increased susceptibility to hydrogen peroxide treatment. We found that the increased expression of ypsA leads to filamentation and disruption of the assembly of FtsZ, the tubulin-like essential protein that marks the sites of cell division in B. subtilis. We also showed that YpsA-mediated filamentation is linked to the growth rate. Using site-directed mutagenesis, we targeted several conserved residues and generated YpsA variants that are no longer able to inhibit cell division. Finally, we show that the role of YpsA is possibly conserved in Firmicutes, as overproduction of YpsA in Staphylococcus aureus also impairs cell division

Worldwide survey of T2* cardiovascular magnetic resonance in Thalassaemia

Introduction Thalassaemia major (TM) affects hundreds of thousands of patients worldwide but only a minority have access to regular blood transfusion and chelation therapy. Cardiovascular magnetic resonance (CMR) T2* measurement provides an accurate, reproducible measurement of cardiac iron which is the cause of heart failure and early death in many transfused TM patients. This technique has been adopted as part of routine management in many countries where survival is now approaching normal but little is known about the severity and effects of myocardial iron loading in different geographical regions. Purpose The aim of this study was to describe the burden of disease of myocardial siderosis (measured by T2*) in different populations throughout the world and to assess the relationship between T2* and outcome such as heart failure and cardiac death. Methods 34 worldwide centres were involved in this survey of 3376 patients from Europe, the Middle East, North America, South America, North Africa, Australia and Asia. Anonymised data on myocardial T2* values were analysed in conjunction with clinical outcomes (heart failure and death). Results Overall, 57.5% of patients had no significant iron loading (T2* >20ms), 22.6% had moderate cardiac iron (10ms50%) in South-East Asia had cardiac iron (T2* >20ms) at baseline. At the time of the first scan, 100 patients (3.3%) had confirmed heart failure, the majority of whom (77.0%) had myocardial T2* <10ms with almost all (99%) having T2* <20ms. There were 113 patients who subsequently developed heart failure. 92.0% of these had T2* <10ms and 99.1% had a T2* <20ms. There were 39 deaths. Cardiac T2* values were <10ms in 79.5%, with 92.3% <20ms. Conclusions Even in this well-treated cohort with access to transfusion, chelation and CMR, there is a large proportion of TM patients with moderate to severe cardiac iron loading. Low T2* (<10ms) is associated with cardiac failure and death. There is a huge unmet worldwide need in terms of access to specialist medical care (including transfusion and chelation therapy) together with advanced monitoring techniques (such as CMR)

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts